Karyopharm Therapeutics Inc. (KPTI) - Dilution Analysis

Visualizing historical and potential share dilution over time

Dilution Analysis

High Risk
Significant dilution risk
Last updated: May 14, 2026

Risk Assessment Details

Potential Dilution: 146.37% of current shares
Recent Dilution: 196704.91% (2 years)
Historical Dilution Factor: significant recent dilution
Outstanding Shares
23M
Potential Supply
33M
Additional shares possible
Splits
1 Split 1 Reverse
Past 2 years

Summary

KPTI currently has 22.7M outstanding shares. with significant dilution risk as 33.2M authorized shares could dilute existing holders by 146.4%. The company has significantly diluted shareholders by 196704.91% over the past 2 years, indicating aggressive capital raising. Recent corporate actions include 1 stock split (positive for accessibility) and 1 reverse split (concerning signal).

Share Structure Timeline

Outstanding Shares
Total Supply

Historical Data Points

Date Event Outstanding Supply
May 14, 2026

10-Q filing | 22.7M shares outstanding

23M 33M
May 04, 2026

S-3 filing: This prospectus relates to the resale from time to time of up to 8,843,036 shares of common stock of Karyopharm Therapeutics Inc. by the selling stockholder listed on page 11, including their donees, pledgees, assignees, transferees or other successors-in-interest, which consist of 1,030,354 outstanding shares of our common stock held by the selling stockholder, 3,391,164 shares of our common stock issuable upon the exercise of outstanding pre-funded warrants held by the selling stockholder and 4,421,518 shares of our common stock issuable upon the exercise of outstanding warrants to purchase shares of our common stock held by the selling stockholder.

8.7M 35M
May 04, 2026

S-3 filing: The company may offer and sell securities from time to time in one or more offerings of up to $400,000,000 in aggregate offering price.

18M 38M
Nov 03, 2025

10-Q filing | 17050.9M shares outstanding

17B 0
Nov 03, 2025

S-3 filing: This prospectus relates to the resale from time to time of up to 9,569,707 shares of common stock of Karyopharm Therapeutics Inc. by the selling stockholders listed on page 13.

8.7M 26M
Aug 11, 2025

10-Q filing | 8.7M shares outstanding

8.7M 4.3M
May 12, 2025

10-Q filing | 8.6M shares outstanding

8.6M 4.3M
Feb 25, 2025
Stock Split

8-K filing: Stock split 1-for-15 | Outstanding: 126,240,054 → 8,416,003

8.4M 4.6M
Feb 19, 2025

10-K filing | 126.2M shares outstanding

130M 68M
Nov 05, 2024

10-Q filing | 125.3M shares outstanding

130M 69M
Aug 06, 2024

10-Q filing | 121.0M shares outstanding

120M 74M
May 30, 2024

S-3 filing: This S-3 filing relates to the resale of up to 45,776,213 shares of common stock issuable upon the exercise of warrants previously issued to selling stockholders in privately negotiated convertible notes exchanges.

120M 79M
May 08, 2024

8-K filing: Karyopharm Therapeutics Inc. entered into agreements to exchange $148.0 million of existing convertible notes for $111.0 million of new secured convertible notes and warrants to purchase up to 46.0 million shares of common stock, along with other financing transactions.

110M 35M
May 08, 2024

10-Q filing | 115.5M shares outstanding

120M 33M
Feb 29, 2024

10-K filing | 114.2M shares outstanding

110M 35M
Nov 02, 2023

10-Q filing | 114.4M shares outstanding

110M 34M
Aug 02, 2023

10-Q filing | 114.2M shares outstanding

110M 35M
May 04, 2023

10-Q filing | 113.5M shares outstanding

110M 35M
Feb 17, 2023

10-K filing | 113.3M shares outstanding

110M 36M
Feb 17, 2023

S-3 filing: The company is filing an S-3 to register the offering and sale of up to $300,000,000 of debt securities, common stock and preferred stock. Additionally, the company may offer and sell shares of common stock up to $100,000,000 from time to time through Jefferies LLC, acting as its sales agent.

80M 69M
Dec 23, 2022

S-3 filing: This S-3 filing registers 41,329,471 shares of common stock for resale by selling stockholders, including 31,791,908 outstanding shares and 9,537,563 shares issuable upon the exercise of outstanding warrants.

80M 41M
Nov 03, 2022

10-Q filing | 80.2M shares outstanding

80M 0
Aug 04, 2022

10-Q filing | 79.7M shares outstanding

80M 0
May 05, 2022

10-Q filing | 79.4M shares outstanding

79M 0
Mar 01, 2022

10-K filing | 79.2M shares outstanding

79M 0
Nov 03, 2021

10-Q filing | 75.5M shares outstanding

76M 0
Aug 05, 2021

10-Q filing | 75.5M shares outstanding

75M 0
May 04, 2021

10-Q filing | 75.1M shares outstanding

75M 0
Feb 24, 2021

10-K filing | 74.6M shares outstanding

75M 0
Nov 02, 2020

10-Q filing | 73.6M shares outstanding

74M 0
Aug 04, 2020

10-Q filing | 73.5M shares outstanding

73M 0
May 05, 2020

10-Q filing | 73.1M shares outstanding

73M 0
Feb 26, 2020

10-K filing | 65.5M shares outstanding

66M 0
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