Spyre Therapeutics, Inc. (SYRE) - Dilution Analysis

Visualizing historical and potential share dilution over time

Dilution Analysis

High Risk
Significant dilution risk
Last updated: May 05, 2026

Risk Assessment Details

Potential Dilution: 89.69% of current shares
Recent Dilution: 62.66% (2 years)
Historical Dilution Factor: significant recent dilution
Outstanding Shares
87M
Potential Supply
78M
Additional shares possible
Splits
None
Past 2 years

Summary

SYRE currently has 86.8M outstanding shares. with significant dilution risk as 77.9M authorized shares could dilute existing holders by 89.7%. The company has significantly diluted shareholders by 62.66% over the past 2 years, indicating aggressive capital raising.

Share Structure Timeline

Outstanding Shares
Total Supply

Historical Data Points

Date Event Outstanding Supply
May 05, 2026

10-Q filing | 86.8M shares outstanding

87M 78M
Aug 05, 2025

10-Q filing | 60.4M shares outstanding

60M 100M
May 08, 2025

10-Q filing | 60.4M shares outstanding

60M 100M
Mar 07, 2025

POS AM filing: This is a post-effective amendment filing to deregister securities from a previous shelf registration statement and sales agreement as the company has terminated all offerings of securities pursuant to the Registration Statement.

60M 100M
Feb 27, 2025

10-K filing | 60.3M shares outstanding

60M 110M
Feb 27, 2025

S-3 filing: The filing relates to an at-the-market offering of common stock with an aggregate offering price of up to $179,059,869. The company intends to use the net proceeds of the offering to advance clinical programs, develop general infrastructure, and potentially in-license or acquire additional businesses, technologies, products, or assets.

60M 110M
Nov 19, 2024

8-K filing: Spyre Therapeutics, Inc. entered into an underwriting agreement for the offer and sale of 7,275,000 shares of common stock at $27.50 per share, with an option for the underwriters to purchase an additional 1,091,250 shares. ($200.0M proceeds)

51M 110M
Nov 07, 2024

10-Q filing | 50.9M shares outstanding

51M 110M
Sep 20, 2024

S-3 filing: The filing registers for resale by the Selling Stockholders 46,330,799 shares, including shares of Common Stock, shares of Common Stock issuable upon the conversion of Series A Preferred Stock, shares of Common Stock issuable upon the conversion of Series B Preferred Stock and shares of Common Stock issuable upon the exercise of Parapyre Warrants.

51M 110M
Sep 06, 2024

S-3 filing: S-3 filing for common stock offering with an aggregate offering price of up to $200,000,000.

51M 65M
Aug 07, 2024

10-Q filing | 50.8M shares outstanding

51M 58M
May 09, 2024

10-Q filing | 36.5M shares outstanding

37M 72M
Apr 19, 2024

S-1 filing: This S-1 filing registers for resale up to 22,496,402 shares of Common Stock and 10,865,000 shares of Common Stock issuable upon the conversion of Series B Preferred Stock by selling securityholders.

36M 73M
Mar 27, 2024

S-1/A filing: This S-1/A filing registers for resale up to 6,000,000 shares of common stock and 6,000,000 shares of common stock issuable upon the conversion of 150,000 shares of Series B Preferred Stock by selling securityholders.

36M 40M
Mar 27, 2024

POS AM filing: This POS AM filing relates to the future sales of shares by existing stockholders and the registration of shares for resale to satisfy obligations under a registration rights agreement.

36M 40M
Mar 14, 2024

S-1/A filing: This S-1/A filing registers for resale up to 6,000,000 shares of Common Stock and 6,000,000 shares of Common Stock issuable upon the conversion of 150,000 shares of Series B Preferred Stock by selling securityholders.

36M 40M
Mar 14, 2024

POS AM filing: This POS AM filing registers the resale of common stock by existing stockholders, including shares issued upon conversion of Series A Preferred Stock, to satisfy obligations under a registration rights agreement.

36M 40M
Mar 05, 2024

POS AM filing: This POS AM filing relates to the resale of common stock by existing stockholders, originally obtained through conversion of preferred stock, and discusses potential dilution and market risks associated with future sales of common stock.

36M 40M
Mar 01, 2024

S-1/A filing: This S-1/A filing registers the resale of up to 6,000,000 shares of Common Stock and 6,000,000 shares of Common Stock issuable upon the conversion of 150,000 shares of Series B Preferred Stock by selling stockholders.

36M 1.1B
Feb 29, 2024

10-K filing | 36.2M shares outstanding

36M 1.1B
Feb 05, 2024

S-1/A filing: This S-1/A filing registers the resale of shares of common stock and common stock issuable upon conversion of Series B Preferred Stock by existing stockholders.

36M 1.1B
Dec 22, 2023

S-1 filing: This S-1 filing registers the resale of common stock by selling stockholders, including shares issuable upon conversion of preferred stock. The company will not receive any proceeds from the sale of these shares.

36M 1.1B
Nov 15, 2023

S-1/A filing: This is an S-1/A filing registering the resale of common stock by selling stockholders.

4.3M 1.2B
Nov 09, 2023

10-Q filing | 4.3M shares outstanding

4.3M 1.2B
Oct 10, 2023

S-1/A filing: This is an S-1/A filing registering resale shares for selling stockholders.

96M 1.1B
Aug 11, 2023

10-Q filing | 95.6M shares outstanding

96M 1.1B
Aug 07, 2023

S-3 filing: This S-3 filing relates to the proposed resale of up to 1,099,284,385 shares of common stock by selling stockholders, consisting of Merger Common Shares, Merger Conversion Shares, and Private Placement Conversion Shares. The company will not receive any proceeds from the sale.

1.1B 64M
May 11, 2023

10-Q filing | 65.4M shares outstanding

65M 0
Mar 02, 2023

10-K filing | 65.4M shares outstanding

65M 0
Nov 03, 2022

10-Q filing | 61.5M shares outstanding

62M 2.1M
Aug 04, 2022

10-Q filing | 61.2M shares outstanding

61M 2.4M
May 05, 2022

10-Q filing | 50.4M shares outstanding

50M 13M
Mar 08, 2022

10-K filing | 49.4M shares outstanding

49M 14M
Nov 04, 2021

10-Q filing | 49.3M shares outstanding

49M 14M
Aug 05, 2021

10-Q filing | 49.1M shares outstanding

49M 15M
May 28, 2021

S-3 filing: This prospectus relates to the sale or other disposition from time to time by the selling stockholder named in this prospectus of up to an aggregate of 19,020,434 shares of our common stock.

49M 15M
May 10, 2021

10-Q filing | 49.0M shares outstanding

49M 0
Mar 18, 2021

10-K filing | 48.0M shares outstanding

48M 0
Nov 05, 2020

10-Q filing | 47.9M shares outstanding

48M 0
Aug 10, 2020

10-Q filing | 44.6M shares outstanding

45M 0
Jul 06, 2020

S-3 filing: Aeglea BioTherapeutics, Inc. may offer up to $400,000,000 aggregate dollar amount of shares of its common stock or preferred stock, debt securities, warrants to purchase common stock, preferred stock or debt securities, subscription rights to purchase common stock, preferred stock or debt securities and/or units consisting of some or all of these securities, in any combination.

45M 0
May 07, 2020

10-Q filing | 44.6M shares outstanding

45M 0
Apr 28, 2020

8-K filing: Aeglea BioTherapeutics, Inc. entered into an underwriting agreement to issue and sell 11,652,830 shares of its common stock and pre-funded warrants to purchase 13,610,328 shares of its common stock at a price of $4.75 and $4.7499 respectively.

29M 0
Feb 24, 2020

10-K filing | 29.1M shares outstanding

29M 0
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